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For the second time in a week, the secretary of state pointed to reports of atrocities in the Ethiopian region.

WASHINGTON — Secretary of State Antony J. Blinken on Tuesday pressed the leader od Ethiopia to end hostilities in the northern Tigray region, citing a “growing number of credible reports of atrocities and human rights violations and abuses.”

In a phone call with Prime Minister Abiy Ahmed, Mr. Blinken pushed for Ethiopia to withdraw outside forces from Tigray, and for an immediate end to the violence, according to a State Department spokesman, Ned Price.

The Biden administration is seeking an end to what it describes as a deepening humanitarian crisis. It was the second time in less than a week that Mr. Blinken cited reports of atrocities in the region.

“The secretary urged the Ethiopian government to take immediate, concrete steps to protect civilians, including refugees, and to prevent further violence,” Mr. Price said in a statement Tuesday.

Speaking to reporters, he said, “We strongly condemn the killings, the forced removals and displacement, the sexual assaults, and other human rights violations and abuses by several parties that multiple organizations have now reported.”

Mr. Blinken also asked that Mr. Abiy allow independent international investigations.

A spokeswoman for Mr. Abiy, Billene Seyoum, pointed to a statement made late last month in which Ethiopia’s Foreign Affairs Ministry called American attempts to intervene in its internal affairs “regrettable.”

The statement said that Ethiopia’s government took its responsibility for the safety, security, and well-being of all citizens “very seriously” and that it was “fully committed to undertake thorough investigations” into reports of abused.

But it added the government had a duty to hold the nation together in the face of “treasonous and divisive forces.”

The Ethiopians military ousted the former local ruling party, the Tigray People’s Liberation Front, from the regional capital in November, after what it described as a surprise assault on its forces in Tigray.

Thousands of people have died, hundreds of thousands have been forced from homes and there are shortages of food, water and medicine around the region of more than five million people.